Estradiol Concentrations and Wellbeing in Trans People Using Estradiol Hormone Therapy

A Ginger; S Zwickl; LM Angus; SY Leemaqz; T Cook; AFQ Wong; AS Cheung

Journal article

Estradiol Concentrations and Wellbeing in Trans People Using Estradiol Hormone Therapy

A Ginger, S Zwickl, LM Angus, SY Leemaqz, T Cook, AFQ Wong, AS Cheung

Transgender Health | MARY ANN LIEBERT, INC | Published : 2024

DOI: 10.1089/trgh.2023.0038

Abstract

Purpose: In trans people undergoing feminizing hormone therapy, optimal estradiol concentrations are unclear, and anecdotally, some individuals desire supraphysiologic estradiol concentrations. We aimed to assess associations between estradiol concentration and psychological distress, well-being, and dysphoria. Second, we aimed to explore relationships between estradiol concentration and the risk of medical conditions potentially associated with estradiol therapy. Methods: This exploratory online cross-sectional study was conducted between June 2020 and March 2021, using a nonprobability snowball sampling method. Inclusion criteria included the following: (1) Currently living in Australia, (..

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University of Melbourne Researchers

Sav Zwickl Author

Ada Cheung Author

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Grants

Funding Acknowledgements

A.S.C. is supported by an Australian Government National Health and Medical Research Council Early Career Fellowship (no. 1143333), Investigator Grant (no. 2008956), and The University of Melbourne Dame Kate Campbell Fellowship. L.M.A. is supported by & nbsp;the Research Training Program Scholarship from the Australian Common wealth Government